Effects of water extract of Radix Isatidison proliferation and differentiation of 3T3-L1 preadipocytes
10.3969/j.issn.1001-1978.2017.08.023
- VernacularTitle:板蓝根水提物对3T3-L1前脂肪细胞增殖和分化的影响
- Author:
Jiping LI
;
Wenyou ZHANG
;
Tingting SUN
;
Yiting FENG
;
Moxiang LIU
- Keywords:
WERI;
3T3-L1 preadipocytes;
proliferation;
differentiation;
PPARγ;
C/EBPα;
fat accumulation
- From:
Chinese Pharmacological Bulletin
2017;33(8):1159-1164
- CountryChina
- Language:Chinese
-
Abstract:
Aim To explore the effect of water extract of Radix Isatidis(WERI)on proliferation and differentiation of 3T3-L1 preadipocytes.Methods 3T3-L1 preadipocytes were cultured to explore the effect of WERI on their proliferation measured by MTT and flow cytometry.Oil red O staining was applied to investigate the effect of different concentrations of WERI on the differentiation of 3T3-L1 preadipocytes.