Clinical analysis on 6 cases of hematological patients with rhino-orbital-cerebral mucormycosis

VernacularTitle:血液病合并鼻-眶-脑型毛霉菌病6例临床分析
Author: Yan SHE ; Xiaolu WANG
Keywords: mucormycosis; nasal endoscopic surgery; hematologic diseases; immunosuppression
From: Medical Journal of Chinese People's Liberation Army 2017;42(7):643-646
CountryChina
Language:Chinese
Abstract: Objectives To explore the clinical characteristics of hematologic disease complicated by rhino-orbital-cerebral mucormycosis (HD-ROCM) and improve the understanding, diagnosis and treatment of M-ROC.Methods For mastering the clinical characteristics, treatment and prognosis of HD-ROCM, the medical records of 6 HD-ROCM patients admitted from 2009 to 2015 were analyzed retrospectively, and related literatures were also retrieved and reviewed.Results All the patients had bone marrow transplantation, 2 out of 6 patients had neutropenia, 5 had endoscopic debridement in a few days to several months after the onset of symptoms, and 1 had open debridement. 3 out of 6 achieved local debridement, and the other 3 had radical debridement. Out of them, one died 8 days postoperation, 1 died at 1 month, 2 at 2 months and 2 at 6 months.ConclusionEarly diagnosis and timely surgical treatment are the key points for improving the survival rate of HD-ROCM patients.