Evaluating mucosal injuries of low-volume PEG plus ascorbic acid regimen in bowel preparation
10.3969/j.issn.1007-1989.2017.07.010
- VernacularTitle:低剂量聚乙二醇联合抗坏血酸方案对肠道黏膜损伤的影响
- Author:
Zheng REN
;
Desheng YANG
;
Hongtao HOU
;
Jinping SUN
;
Yuhua KANG
;
Chunsheng DING
- Keywords:
polyethylene glycols;
sodium phosphate;
bowel preparation;
mucosal injuries
- From:
China Journal of Endoscopy
2017;23(7):46-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the bowel-cleansing efficacy, patient security and mucosal injury of low-volume PEG plus ascorbic acid regimen. Methods Five hundred patients referred for colonoscopy were enrolled and randomly divided into two groups. Group A received low-volume PEG regimen, Group B received sodium phosphate (NaP) regimen for bowel preparation. Patients of the two groups drank solution 5 h before colonoscopies, serum creatinine and electrolyte were monitored at 5 h and 3 h before colonoscopies. The bowel-cleansing efficacy was rated during colonoscopy. All mucosal injuries observed during colonoscopy were biopsied and histopathologically reviewed. Results The patients of group A completed bowel preparation of 233 cases, completed colonoscopy 226 Cases, group B completed bowel preparation 238 cases, completed colonoscopy 210 cases. There was no significant difference in bowel cleansing between the groups (P > 0.05). Group A reported less incidence rate of the mucosal injuries than Group B. Group A reported better patient security than Group B at the same time. Conclusion Compared with sodium phosphate (NaP) regimen low-volume Polyethylene Glycol (PEG) plus ascorbic acid regimen exhibited equivalent bowel-cleansing efficacy and less incidence rate of the mucosal injuries and better patient security.
