Efficacy of endoscopic therapy in treatment of esophageal gastric varices bleeding in patients with hepatocellular carcinoma and portal vein tumor thrombus
10.3969/j.issn.1007-1989.2017.07.014
- VernacularTitle:内镜治疗肝癌合并门静脉癌栓引起的食管胃底静脉曲张出血的疗效分析
- Author:
Jun LI
;
Lifeng DONG
;
Ping LI
- Keywords:
endoscopic therapy;
hepatocellular carcinoma;
portal vein tumor thrombus;
esophageal gastric varices bleeding
- From:
China Journal of Endoscopy
2017;23(7):66-70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect and survival period of endoscopic treatment group and non endoscopic treatment group of esophageal gastric varices bleeding in patients with hepatocellular carcinoma and portal vein tumor thrombus, in order to define the significance of endoscopic therapy for prolonging the survival period of patients. Methods 76 patients diagnosed as esophageal gastric varices bleeding with hepatocellular carcinoma and portal vein tumor thrombus from Jan. 2013 to Dec. 2015 were enrolled, of all these cases, 27 were non endoscopic treatment group and 49 were endoscopic treatment group. The medical records were analyzed retrospectively. Then compare the effect of emergency treatment, the main causes of death and survival time of the two groups. Results In the non endoscopic treatment group, 40.7% (11/27) patients died in one week after bleeding, 81.5% (22/27) patients died of esophageal gastric varices bleeding, the mean survival period was (42.03 ± 13.94) days; In the endoscopic treatment group, only 16.3% (8/49) patients died in one week (P < 0.05), 55.1% (27/49) patients died of esophageal gastric varices bleeding (P < 0.05), the mean survival time was (174.24 ± 34.42) days (P < 0.05). Conclusions Endoscopic therapy can effectively reduce the risk of death from acute hemorrhage and prolong the survival time in patients with hepatocellular carcinoma and portal vein tumor thrombus.
