Clinical analysis of adult rhabdomyosarcoma of the larynx

VernacularTitle:成人喉部横纹肌肉瘤临床分析
Author: Zheng YANG ; Jugao FANG ; Qi ZHONG ; Xuejun CHEN ; Zhigang HUANG
Keywords: Laryngeal Neoplasms; Sarcoma; Rhabdomyosarcoma; Diagnosis; Prognosis
From: Chinese Archives of Otolaryngology-Head and Neck Surgery 2017;24(6):275-278
CountryChina
Language:Chinese
Abstract: OBJECTIVE To summarize the clinical features, diagnosis, treatment and prognosis of laryngeal rhabdomyosarcoma.METHODS The clinical data of 5 cases of adult laryngeal rhabdomyosarcoma treated in Beijing Tongren Hospital between 2003 and 2015 were analyzed retrospectively.RESULTS All the 5 cases firstly presented with hoarseness. 1 case was treated by combined therapy (surgery followed by radiotherapy and chemotherapy). 2 patients received surgical treatment combined with chemotherapy. 1 patient received surgical treatment only. Another patient received chemotherapy only. Pathological type: 4 patients were embryonal rhabdomyosarcoma, 1 patient was pleomorphic rhabdomyosarcoma. In the follow-up of a period from 11 months to 8 years, 2 cases were alive without tumor, 3 patients were dead.CONCLUSION Adult laryngeal rhabdomyosarcoma is rare. Surgical resection combined with chemotherapy is the main treatment method, and the prognosis is related to the pathological type and tumor stage.