Therapeutic Observation of Ginger-partitioned Moxibustion in Treating Myelosuppression Induced by Chemotherapy for Multiple Myeloma
10.13460/j.issn.1005-0957.2017.07.0816
- VernacularTitle:隔姜灸治疗多发性骨髓瘤化疗所致骨髓抑制疗效观察
- Author:
Wanbing LIN
;
Jieying ZHOU
;
Bei JIANG
;
Ying SHI
- Keywords:
Moxibustion;
Ginger-partitioned moxibustion;
Multiple myeloma;
Chemotherapy;
Myelosuppression;
White blood cell count;
Partitioned moxibustion
- From:
Shanghai Journal of Acupuncture and Moxibustion
2017;36(7):816-820
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of ginger-partitioned moxibustion in treating myelo- suppression induced by chemotherapy for multiple myeloma (MM), and to discuss the effect of ginger-partitioned moxibustion in preventing and treating the adverse reactions of chemotherapy.Method Forty-four MM patients with myelosuppression induced by chemotherapy were randomized into a treatment group and a control group, 22 cases each. The treatment group was intervened by ginger-partitioned moxibustion, while the control group was intervened by oral administration of Leukogen tablets, both for 14 d. The white blood cell (WBC) count was observed before the treatment, on treatment day 7 and 14, and 1 week after the intervention; the incidence of nausea and vomit and clinical efficacies were compared between the two groups.Result The total effective rate was 81.8% in the treatment group versus 63.6% in the control group, and the difference was statistically significant (P<0.05). The WBC count on the 7th treatment day was significantly different from that before the treatment in both groups (P<0.05); the WBC count in the treatment group was significantly different from that in the control group on the 7th treatment day (P<0.05). The WBC count on the 14th treatment day was significantly different from that on the 7th day in both groups(P<0.05); the WBC count in the treatment group was significantly different from that in the control group on the 14th treatment day (P<0.05). The WBC count 1 week after the treatment was insignificantly different from that on the 14th treatment day in both groups (P>0.05); there was no significant difference in comparing the WBC count 1 week after the treatment between the two groups (P>0.05). The incidence of nausea and vomit in the treatment group was significantly lower than that in the control group after the treatment (P<0.05).Conclusion Ginger-partitioned moxi- bustion can effectively treat myelosuppression due to chemotherapy for MM, and it can significantly increase the WBC count.
