Diagnostic value of prostate imaging reporting and data system version 1 and 2 in detection of prostate cancer in transition zone
10.3760/cma.j.issn.1005-1201.2017.06.006
- VernacularTitle:第一版和第二版前列腺影像报告和数据系统评分对移行带前列腺癌的诊断价值
- Author:
Ximing WANG
;
Jie BAO
;
Mo ZHU
;
Xiaoxia PING
;
Chunhong HU
;
Jianquan HOU
;
Qilin XI
;
Fenglin DONG
;
Jun SUN
;
Wenlu ZHAO
;
Junkang SHEN
- Keywords:
Prostatic neoplasms;
Magnetic resonance imaging;
Prostate imaging reporting and data system;
Comparative study
- From:
Chinese Journal of Radiology
2017;51(6):427-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of prostate imaging reporting and data system version 1 (PI-RADS V1) and version 2 (PI-RADS V2) for detection of prostate cancer (PCa) in the transition zone (TZ).Methods Seventy-seven patients with suspicious lesions in TZ on mpMRI were scored according to the PI-RADS system (V1 and V2) before MR-TRUS fusion guided biopsy prospectively.In all of the patients with suspicious tumors,respectively at least one lesion with a PI-RADS V1 assessment category of ≥3,was selected for biopsy.Independent sample t test was used to compare scores of PI-RADS V1 and V2 between PCa and benign prostatic hyperplasia (BPH).The diagnostic performance of PI-RADS V 1 and V2 for detection of PCa in the transition zone was compared by analyzing ROC basing on the results of MR-TRUS fusion guided biopsy.Results A cohort of 77 patients was performed including 31 cases of PCa (32 cores) and 46 cases of BPH (51 cores).PCa (V1:1 1.50±2.79;V2:4.28±0.99) had significantly higher scores of both PI-RADS V1 and PI-RADS V2 than BPH(V1:7.51± 1.63;V2∶2.61 ±0.67) (P＜0.05).Using a PI-RADS V1 score cut-off ≥ 11,sensitivity and specificity in group PCa and BPH were calculated,which were 68.8％(22/32) and 96.1％(49/51) with a area under curve of 0.869;using a PI-RADS V2 score cut-off ≥4,which were 75.0％ (24/32) and 90.2％ (46/51) with a area under curve of 0.888,respectively.Conclusions PI-RADS system can indicate the likelihood of PCa of suspicious lesions in TZ on Mp-MRI.PI-RADS V2 perform better than V 1 for the assessment of prostate cancer in TZ.
