Generalized linear model analysis of the relationship of four kinds of prenatal lifestyle factors and congenital heart disease
10.7652/jdyxb201703003
- VernacularTitle:围孕期妇女4种生活因素与新生儿先天性心脏病关系的广义线性模型分析
- Author:
Ruo ZHANG
;
Hui MA
;
Hui YAN
;
Yaqin WANG
;
Yang MI
;
Fangyao CHEN
;
Pengfei QU
;
Shanshan LI
;
Shaonong DANG
;
Hong YAN
- Keywords:
prenatal lifestyle factor;
congenital heart disease;
case-control study;
generalized linear model
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2017;38(3):332-336
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of four kinds of lifestyle factors,namely,prenatal passive smoking,hair dyeing or perming,exposure to noise,living in a house renovated in the past one year,with congenital heart disease.Methods A hospital-based case-control study was conducted.Totally 270 mothers in the case group and 1633 mothers in the control group were interviewed through a face-to-face questionnaire survey.A generalized linear model was employed to investigate the association between congenital heart disease and prenatal lifestyle factors.Results Both in Model 1 and Model 2,prenatal hair dyeing or perming had no association with congenital heart disease.On the other hand,prenatal passive smoking,exposure to noise and living in a house renovated in the past one year all increased the risk of congenital heart disease.After adjustment for all confounders,the OR values were 1.771 (95％ CI:1.079-2.909),2.079 (95％ CI:1.310-3.298),and 2.494 (95％ CI:1.511-4.116),respectively.Conclusion Prenatal passive smoking,exposure to noise and living in a house renovated in the past one year are the risk factors for congenital heart disease.It is very important to avoid such factors during pre-pregnancy and pregnancy.
