Advances of new excipients and technique in colon-specific preparations
10.11665/j.issn.1000-5048.20170217
- VernacularTitle:新辅料和新技术在结肠定位制剂中的应用
- Author:
Shina SU
;
Zhufen LYU
;
Chaofeng LIANG
;
Kewei LU
;
Yunran HUANG
;
Yanzhong CHEN
- Keywords:
oral colon-specific drug delivery system;
excipients;
technique;
application
- From:
Journal of China Pharmaceutical University
2017;48(2):242-250
- CountryChina
- Language:Chinese
-
Abstract:
The oral colon-specific drug delivery system (OCDDS) has gained more attention from investigators in recent years since it can increase local drug concentration and reduce dosage and side effects.The type of colonspecific drug delivery system consists of enzyme dependent,pH dependent,time dependent,pressure dependent system and CODEDSTM.The development of many new materials and technology is very important for the preparation of new type of precise positioning colon-specific preparation.This article summarizes the advances in excipients and technique for oral colon-specific drug delivery system in recent years.It may provide a reference and a basis for the researchers concerned.
