Research advances of the role of inflammatory responses in ARDS

VernacularTitle:炎症反应在ARDS中的作用机制研究进展
Author: Liuyang HE ; Jianzhou ZHENG ; Lei XIA ; Chunjian QI ; Yong WANG ; Mingxia YANG
Keywords: Acute lung injury; Acute respiratory distress syndrome; Inflammation; Cytokine
From: Chinese Critical Care Medicine 2017;29(7):651-655
CountryChina
Language:Chinese
Abstract: Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is an inflammatory lung injury induced by a variety of factors, and these diseases are associated with high rates of mortality due to the lack of effective treatments. Based on the latest research in ALI/ARDS, it is widely accepted that generalized inflammatory responses play a critical role in initiating and developing process of ALI/ARDS. We make a brief review on the immune-pathogenesis and the signaling pathways of ALI/ARDS from the perspective of inflammation, thereby helping develop novel therapeutic strategy for treatment of patients with ALI/ARDS.