Effect of CRRT on the clearance of antibiotics in the treatment of sepsis
10.3760/cma.j.issn.2095-4352.2017.07.019
- VernacularTitle:CRRT对脓毒症治疗中抗菌药物清除作用的影响
- Author:
Jingjing ZONG
;
Chunsheng LIU
;
Xiaofei FU
;
Jingchao ZHOU
;
Dan WANG
- Keywords:
Sepsis;
Continuous renal replacement therapy;
Antibiotics;
Clearance
- From:
Chinese Critical Care Medicine
2017;29(7):662-665
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis should be defined as life-threatening organ dysfunction caused by a dys-regulated host response to infection. Continuous renal replacement therapy (CRRT) is one of the methods for the clinical treatment of sepsis. For patients undergoing CRRT, rational antimicrobial therapy is very important for the control of patient's infection. However, during CRRT, there is no clear guideline for the dose adjustment of antibiotics. In this paper, we analyzed the effect of CRRT combined with antibiotics on sepsis treatment in China and abroad, and discussed its effect on antibiotic clearance, and provided reference for clinical work.
