Role of 5-hydroxytryptamine in the pathogenesis and treatment of nonalcoholic fatty liver disease
10.3969/j.issn.1001-5256.2017.06.033
- VernacularTitle:5-羟色胺在非酒精性脂肪性肝病发病机制及治疗中的作用
- Author:
Dou JIN
;
Chunyan NIU
- Keywords:
fatty liver;
serotonin;
review
- From:
Journal of Clinical Hepatology
2017;33(6):1169-1172
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence rate of nonalcoholic fatty liver disease (NAFLD) has been increasing year by year.However,since the complex pathogenesis of NAFLD has not been fully clarified,there still lacks a gold standard for the diagnosis and treatment of NAFLD.5-Hydroxytryptamine (5-HT) can affect the development and progression of NAFLD via several links and thus change the course of NAFLD.This article introduces the association between 5-HT and NAFLD,the role of 5-HT in the pathogenesis of NAFLD,and its future application in treatment.