Research on Clinical Significance of Serum CRP and SAA in Patients with Chronic Obstructive Pulmonary Disease after Comprehensive Assessment and Correlation with Lung Function.
10.11969/j.issn.1673-548X.2017.06.037
- VernacularTitle:血清CRP、 SAA对慢性阻塞性肺疾病患者综合评估的意义及与肺功能的相关性研究
- Author:
Xiaohua HE
;
Yuanrong DAI
;
Qiuxiang SONG
- Keywords:
Chronic obstructive pulmonary disease;
C-reactive protein;
Serum amyloid protein A;
Lung function
- From:
Journal of Medical Research
2017;46(6):144-146,150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of serum CRP and SAA in patients with comprehensive assessment COPD group,and correlation with lung function.Methods We selected 139 cases patients with COPD.According to the guide of GOLD 2015,the COPD patients were divided into group A (23 cases),group B (19 cases),group C (51 cases) and group D (46 cases).Analysis of the correlation between serum CRP and SAA level and injury severity of pulmonary function was perforined.Results Compared with group A,C,the group D had significance and had the highest level of serum CRP,SAA (P < 0.05).Group B was higher than group C.The Lung function damage degree was negatively correlated with the level of CRP and SAA in patients with COPD (P < 0.05).Conclusion The change of the concentration of serum CRP,SAA will contribute to the evaluation of patients with COPD and provide objective basis for the treatment and management of patients with COPD.Detection of CRP,SAA is helpful to evaluate the damage degree of lung function.