New advances in the application of oncolytic virus for the treatment of glioma
10.3760/cma.j.issn.1008-6315.2017.06.021
- VernacularTitle:溶瘤病毒在治疗胶质瘤中的应用新进展
- Author:
Da QIAN
;
Chuanlu JIANG
- Keywords:
Glioma;
Oncolytic virus;
Mechanism;
Treatment
- From:
Clinical Medicine of China
2017;33(6):557-560
- CountryChina
- Language:Chinese
-
Abstract:
Glioma is the most common primary malignant tumor in the brain.Although through standardized treatment,including the largest range of surgical resection and subsequent radiotherapy and chemotherapy,the morbidity and mortality is still high,so we need a new treatment.The oncolytic virus antitumor concept was mentioned in the early 20th century,which is a kind of antitumor virus,people found that cancer patients infected with certain viruses,the tumor was gradually disappeared.With the development of Molecular Biology,Immunology,Virology and Genetic Engineering,oncolytic virus becomes a new method of tumors treatment,which attracts more and more researchers' attention,so we made an overview in the antitumor principle of oncolytic virus and its clinical application in the treatment of glioma.
