The value of the combined detection of IMA, NT-proBNP and dynamic electrocardiogram in the diagnosis of silent myocardial ischemia
10.3969/J.ISSN.1672-8270.2017.09.023
- VernacularTitle:缺血修饰白蛋白和氨基末端脑钠肽前体联合动态心电图在无症状心肌缺血诊断中的价值
- Author:
Wen DU
;
Guixiang ZHAO
- Keywords:
Silent myocardial ischemia;
Ischemia modified albumin;
N-terminal pro brain natriuretic peptide;
Dynamic electrocardiogram;
Coronary artery fabrication
- From:
China Medical Equipment
2017;14(9):85-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical value of combined detection of ischemia modified albumin(IMA), N-terminal pro brain natriuretic peptide(NT-proBNP) and dynamicelectrocardiogram(DEG) in the diagnosis of silent myocardial ischemia.Methods: IMA, NT-proBNP and DEG of 114 patients with silent myocardial ischemia who were suspected coronary heart disease were detected, and then these results were compared and analyzed with the results of coronary angiography(CAG).Results: In 114 patients with suspected coronary heart disease, 68 cases(59.65％)were positive as the results of CAG. And there were 60 cases were positive as the results of IMA detection, and the specificity and sensitivity of IMA compared with CAG were 82.61％ and 88.24％, respectively. There were 63 cases were positive as the results of NT-proBNP, and the specificity and sensitivity of NT-proBNP compared with CAG were 80.43％ and 92.64％, respectively. There were 57 cases were positive as the results of DEG, and the specificity and sensitivity of DEG compared with CAG were 86.96％ and 83.82％, respectively. While there were 66 cases were positive as the combined detection of the three methods, and specificity and sensitivity of the combined detection compared with CAG were 95.65％ and 97.06％, respectively. Therefore, the specificity and sensitivity of combined detection were significantly higher than that of alone detection of IMA, NT-proBNP and DEG (F=140.637,F=255.467,P<0.05).Conclusion: The comprehensive analysis for the combined detections of IMA, NT-proBNP and DEG can increase both of the specificity and sensitivity of diagnosis, and it can be used as a important screening method for earlier finding silent myocardial.
