Research progress on bifidobacterium-mediated genetic engineering vaccines against parasites
10.3760/cma.j.issn.2095-4255.2017.08.017
- VernacularTitle:双歧杆菌介导的寄生虫基因工程疫苗研究进展
- Author:
Junchao SUN
- Keywords:
Parasitosis;
Bifidobacterium;
Genetic engineering;
Vaccine
- From:
Chinese Journal of Endemiology
2017;36(8):611-616
- CountryChina
- Language:Chinese
-
Abstract:
Parasitosis is one of the most serious infectious diseases endangering human and animal health. Vaccination was an economic and effective measure in prevention and treatment of the disease. Bifidobacterium (Bb) is a kind of important probiotics in intestinal tract of human and other animals. In recent years, with the development of genetic engineering technology, Bb has been selected as a carrier delivery system to construct a series of recombinant Bb, such as in bacteria, viruses, parasites, tumor and other fields. In this review, we reported the preparation and immune effect of several kinds of Bb-mediated genetic engineering vaccines against parasites.
