Drug resistance analysis of Escherichia coli clinical strains
10.3969/j.issn.1673-4130.2017.17.011
- VernacularTitle:大肠埃希菌临床分离株的耐药性分析
- Author:
Wenjun LI
- Keywords:
Escherichia coli;
drug resistance;
nosocomial infection
- From:
International Journal of Laboratory Medicine
2017;38(17):2362-2364
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the change trend of drug resistance in clinical strains of Escherichia coli,and to provide the basis for rational use of antibiotics in clinic,and to increase the level of drug resistance.Methods The drug resistance of Escherichia coli isolated from various clinical specimens in hospital from January 2012 to November 2016 were analyzed retrospectively.Results From all kinds of clinical specimens 3 458 strains of Escherichia coli were isolated,extended spectrum beta-lactamases producing rate of which was 57.92％.The drug resistance rates of Escherichia coli to Quinolones,Penicillins,Cephalosporins,Aminoglycosides,Sulfonamides were more than 50.00％;The resistance rate of Imipenem,Meropenem,Piperacillin/Tazobactam,Cefoperazone/Sulbactam and Cefoxitin were less than 10.00％ of the antibacterial drugs,the resistance to some third,forth generation Cephalosporins were significantly increased.The Wilcoxon test showed that drug resistance rate of Escherichia coli isolated from sputum was significantly higher than that of blood,urine,secretions,the difference was statistically significant(P<0.05).Conclusion Clinicians should attach great importance to which the drug resistance of Escherichia coli in a hospital increased year by year.
