The role of IL-17 in tumor angiogenesis and metastasis
10.16571/j.cnki.1008-8199.2017.09.022
- VernacularTitle:IL-17在肿瘤血管生成和转移中的作用
- Author:
Yue ZHAO
;
Guoqing LIANG
- Keywords:
IL-17;
Th17 cells;
Tumor angiogenesis;
Tumor metastasis
- From:
Journal of Medical Postgraduates
2017;30(9):1004-1008
- CountryChina
- Language:Chinese
-
Abstract:
Th17 cells have recently emerged as a third independent helper T(Th) cell subset that is different from the classical Th1 and Th2 cells.Th17 cells can specifically secrete IL-17 and play an important role in tumorigenesis and metastasis.In this article, we review the origin and differentiation regulation of Th17 cells, the relationship between IL-17 and tumor microenvironment, angiogenesis and metastasis, and try to provide a new direction for the diagnosis and treatment of tumor.
