A Meta-analysis of randomized controlled trials on Xipayi Mouth Rinse for the treatment of halitosis
10.3969/j.issn.1001-3733.2017.01.024
- VernacularTitle:西帕依固龈液治疗口臭随机对照试验的Meta分析
- Author:
Yikun ZHOU
;
Jie ZHANG
;
Ze HE
;
Qiaoyi CAI
;
Xinyu WU
;
Chunguang LI
- Keywords:
Xipayi Mouth Rinse;
Halitosis;
Systematic review;
Meta-analysis
- From:
Journal of Practical Stomatology
2017;33(1):109-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effectiveness of Xipayi Mouth Rinse in the treatment of halitosis.Methods:PubMed/MEDLINE,China National Knowledge Infrastructure (CNKI) (1979-2015) and Weipu Database for Chinese Technical Periodicals (1989-2013) were systemically searched.The methodological quality of the included trials was assessed based on the Jadad scale and the available data were analyzed with RevMan software (version 5.3).Results:8 studies involving 608 participants satisfied the minimum criteria for Meta-analysis.The evidence showed that the Organoleptic Score (OS) of Xipayi Mouth Rinse compared with placebo for treatment of halitosis was [WMD =-0.43,95% CI (-0.57,-0.29)],plaque index (PLI) [WMD =-1.59,95% CI (-1.67,-1.51)];the OS of Xipayi Mouth Rinse compared with western medicine [WMD =0.16,95% CI (0.05,0.28)],PLI [WMD =0.10,95% CI(0.03,0.18)];the total efficiency of Xipayi Mouth Rinse compared with normal saline was[RR:1.64,95% CI(1.11,2.42)].Conclusion:The current clinical evidence showed that the effectiveness of Xipayi Mouth Rinse in the treatment of halitosis is higher than the Placebo,but lower than western medicine.