Clinical study of ziprasidone in the treatment of 78 patients with first-episode schizophrenia

VernacularTitle:齐拉西酮治疗首发精神分裂症78例临床研究
Author: Miaohong ZHUANG ; Jianlin WANG ; Yongfa WU ; Juner YUE ; Caixia LIN ; Yan XU
Keywords: first-episode schizophrenia; risperidone; ziprasidone; clinical efficacy
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(6):170-171,174
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical efficacy of ziprasidone in the treatment of first-episode schizophrenia.Methodsfrom January 2014 to June 2016to receive the treatment of patients with first-episode schizophrenia in 156 cases as the research object in the psychiatric hospital, which were randomly divided into two groups, the control group were given risperidone treatment, the observation group was treated with ziprasidone treatment, compared two groups of clinical curative effect of the treatment of patients after.ResultsThe patients in the observation group the total effective rate was 97.4%, the control group total effective rate was 89.7%;group after treatment in patients with negative symptoms score were significantly lower than the control group, with statistical significance between the two groups (P<0.05).ConclusionThe application of ziprasidone in the treatment of first-episode schizophrenia has achieved good clinical efficacy, the total effective rate of treatment is higher, and the negative symptoms are effectively controlled.