Effect of Xuanfei Zhike Pingchuan decoction combined with budesonide in the treatment of AECOPD and its influence on inflammatory factors and pulmonary function
10.3969/j.issn.1005-1678.2017.06.055
- VernacularTitle:自拟宣肺止咳平喘汤联合布地奈德治疗AECOPD的效果及对炎症因子和肺功能的影响
- Author:
Jianrong FEI
;
Jiawei ZHU
- Keywords:
Xuanfei Zhike Pingchuan decoction;
budesonide;
inflammatory factors;
pulmonary function
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):147-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of Xuanfei Zhike Pingchuan decoction combined with budesonide in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods84 patients with AECOPD in our hospital from June 2014 to June 2016 were selected and randomly divided into the observation group and the control group.The control group was given budesonide and the observation group on the basis of the control group was given Xuanfei Zhike Pingchuan decoction.The clinical efficacy, the levels of inflammatory cytokines and pulmonary function were compared between the two groups.ResultsThe total effective rate for clinical treatment in the observation group was significantly higher than the control group(P<0.05).The levels of IL-6 and TNF-α in the observation group after treatment were significantly lower than the control group (P<0.05),while the levels of FEV1% and FEV1/FVC were obviously higher than the control group (P<0.05).ConclusionXuanfei Zhike Pingchun decoction combined with budesonide on ARCOPD has a significantly curative effect and can effectively improve the inflammatory response and recovery of pulmonary function.
