Clinical prevent effect of taking drospirenone and ethinylestradiol tablets on intrauterine adhesion after missed abortion curettage with b-ultrasonic observation
10.3969/j.issn.1005-1678.2017.06.068
- VernacularTitle:B超监测下稽留流产清宫术后服用屈螺酮炔雌醇片对宫腔粘连的临床预防效果
- Author:
Changyuan ZHU
- Keywords:
B-ultrasonic observation;
missed abortion curettage;
drospirenone and ethinylestradiol tablets;
intrauterine adhesion
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):183-184,187
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss clinical efficacy of taking drospirenone and ethinylestradiol tablets in preventing intrauterine adhesion after missed abortion curettage with b-ultrasonic observation.Methods216 cases of study objects provided with missed abortion curettage with b-ultrasonic observation were divided into control group with 108 cases and research group with 108 cases.Patients in control group were provided with conventional treatment after surgery, while those in research group were provided with conventional treatment and drospirenone and ethinylestradiol tablets.Two groups were compared for condition after surgery such as intrauterine adhesion in 1month after treatment, secondary pregnancy, infertility and abortion in 1 year after treatment.ResultsTime of vaginal bleeding, pelvic effusion and time of return of menses in research group were significantly lower than those in control group, with difference having statistical significance (t=6.114,t=9.481,t=9.201,P<0.05).Endometrial thickness of research group was distinctly greater than control group, with difference having statistical significance (t=14.171,P<0.05).In 1 week and 2 weeks after treatment, the proportion of uterus adhesion in control group was higher than that in research group, with difference having statistical significance (χ2=5.329,χ2=6.051,P<0.05).The difference in rate of secondary pregnancy in 1 year after treatment between two groups had no statistical significance (χ2=0.113,P>0.05).In the case of infertility rate and rate of abortion in 1 year after treatment, control group was higher than research group with difference having statistical significance (χ2=4.317,χ2=5.225,P<0.05).ConclusionTaking drospirenone and ethinylestradiol tablets after missed abortion curettage with b-ultrasonic observation can effectively prevent intrauterine adhesion, which can also reduce complications such as abortion and infertility, therefore, it shall be applied in accordance with specific condition of patients.