Efficacy and safety of Wenxin granule combined with metoprolol in the treatment of arrhythmia in elderly patients with coronary heart disease
10.3969/j.issn.1005-1678.2017.06.123
- VernacularTitle:稳心颗粒联合美托洛尔治疗老年人冠心病心律失常的疗效及其安全性分析
- Author:
Guoju WANG
;
Yunhai CHEN
;
Lijuan MAO
- Keywords:
Wenxin granule;
metoprolol;
arrhythmia of coronary heart disease;
curative effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):325-327
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of Wenxin Granule Combined with metoprolol in the treatment of arrhythmia in elderly patients with coronary heart disease.Methods84 cases of elderly patients with coronary heart disease arrhythmia treated in our hospital from April 2014 to May 2016, were randomly divided into observation group and control group, 42 cases in each group.The observation group was given the Wenxin Granule Combined with metoprolol treatment, the control group were treated with metoprolol,The changes of systolic status, the ischemic condition, hemodynamic changes and plasma viscosity were compared before and after treatment between the two groups, and the clinical effect after treatment were compared.ResultsAfter treatment, two groups of patients with atrial premature contraction, ventricular premature contractions and junctional premature contractions were decreased, the observation group was lower than the control group, the difference between the two groups was statistically significant (P<0.05);After treatment, two groups of patients with ischemic frequency were reduced, the observation group (5.45±1.12)times was lower than the control group (8.12±2.70)times, the difference between the two groups was statistically significant (P<0.05);After treatment, the two groups of patients with total ischemic time is shortened, the observation group (16.45±3.87)min shorter than the control group (22.45±4.89)min, the difference between the two groups was statistically significant (P<0.05);The total effective rate of the observation group was 92.85% higher than the control group (69.20%), the difference was statistically significant(P<0.05).ConclusionElderly patients with coronary heart disease arrhythmia patients with Wenxin granule combined with metoprolol treatment, can effectively improve the clinical symptoms of patients with significant effect.
