Comparison of clinical efficacy between clopidogrel and clopidogrel in the treatment of coronary heart disease with myocardial ischemia
10.3969/j.issn.1005-1678.2017.06.139
- VernacularTitle:替格瑞洛与氯吡格雷治疗冠心病心肌缺血的临床疗效对比
- Author:
Xiaolei HE
;
Li YANG
;
Wen SUN
- Keywords:
Coronary heart disease;
myocardial ischemia;
Grillo;
clopidogrel
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):364-365,368
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy of clopidogrel and clopidogrel in the treatment of myocardial ischemia in patients with coronary heart disease (CHD).Methods86 patients with myocardial ischemia of coronary heart disease from January 2016 to January 2017 in our hospital, were randomly divided into group A (n=43) and group B (n=43), group A was treated with ticagrelor treatment, group B was treated with clopidogrel treatment, clinical curative effect were compared between the two groups.ResultsThe total effective rate in group A was 86.04% was significantly higher than 72.09% in group B, the difference was statistically significant (P<0.05);The number of ST segment descent in group A was (36.17±4.22) times,ST segment continuous decline time (120.29 ±13.53) s ST continued to decline time (120.29±13.53) s, heart rate (65.27±3.18) times/min, systolic blood pressure (105.44±2.17) mmHg, diastolic blood pressure (63.11±3.14) mmHg were significantly lower than the control group (P<0.05);group A patients with triglyceride,total cholesterol,plasma viscosity trimming rate, whole blood viscosity at low shear rate, and whole blood high shear rate were significantly lower than those in group B (P<0.05).ConclusionCompared with clopidogrel, Grillo can effectively improve the blood microcirculation of myocardial ischemia in patients with coronary heart disease, coronary heart disease,relieve myocardial ischemia caused by coronary heart disease The clinical efficacy is remarkable, and it has the value of popularization and Application.
