Effects of sperm morphology, sperm DNA fragment index and seminal plasma zinc on pregnancy outcome of IVF-ET
10.3969/j.issn.1005-1678.2017.06.141
- VernacularTitle:精子形态、精子DNA碎片指数和精浆锌对体外受精-胚胎移植妊娠结局的影响
- Author:
Songcheng GAO
;
Chunyu XIE
;
Yan CHEN
;
Aiping WANG
- Keywords:
sperm morphology;
sperm DNA fragmentation index;
seminal plasma zinc;
IVF-ET;
pregnancy outcome
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):369-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of sperm morphology, sperm DNA fragmentation index and seminal plasma zinc on pregnancy outcome of in vitro fertilization and embryo transfer (IVF-ET).MethodsA total of 341 infertile couples underwent IVF-ET were selected from January 2016 to June 2016 in our hospital.Sperm morphology, sperm DNA fragmentation index and seminal plasma zinc level were compared according to pregnancy.ResultsIn 341 cases, 204 cases pregnancy and 137 cases of no pregnancy, with the pregnancy rate of 59.8%(204/341).Compared with the pregnancy group, the percentage of normal sperm percentage was low, the abnormal sperm index was higher in the non-pregnant group (P<0.05), the sperm DNA index was higher (P<0.05).The percentage of normal sperm, sperm DNA fragmentation index and seminal plasma zinc and pregnancy rate in sperm morphology were linear (P<0.05), And there was a negative correlation between abnormal sperm index and sperm DNA fragment index (P<0.05), and other indicators were positively correlated (P<0.05).ConclusionSperm morphology, sperm DNA fragmentation index and seminal plasma zinc levels may influence the outcome of IVF-ET.The above parameters can be used to predict pregnancy outcome of IVF-ET.
