Clinical significance of S-100B protein in children with different degrees of amniotic fluid meconium contamination
10.3969/j.issn.1005-1678.2017.06.150
- VernacularTitle:S-100B蛋白的测定在不同程度羊水胎粪污染患儿中的临床意义
- Author:
Lina QI
;
Haiying SUN
;
Mingqiang SI
;
Chang SU
- Keywords:
S-100B protein;
the amniotic fluid meconium pollution;
brain damage
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):393-394
- CountryChina
- Language:Chinese
-
Abstract:
Objective Detection of S-100B protein in different degree meconium pollution level in serum of children with value.MethodsIn 2012 June to 2013 December in our department were simple meconium stained amniotic fluid in term newborns in 73 cases, and set up for the observation group, and according to the amniotic fluid pollution degree is divided into 47 cases of amniotic fluid of Ⅰ-Ⅱdegree pollution group and 26 cases in grade Ⅲmeconium group during the same period, selected 20 cases without amniotic fluid contamination in term healthy newborns for the control group, the groups were compared in S-100B protein content difference.ResultsⅢmeconium stained amniotic fluid were within 6h serum S-100B was significantly higher than that in control group(P<0.01), and the degree of contamination of amniotic fluidⅠ-Ⅱgroup compared with the control group, no significant difference(P>0.05).Ⅲ meconium stained amniotic fluid in children with 72h also increased.ConclusionThird degree meconium stained amniotic fluid but normal Apgar score of newborns may still exist in clinical brain injury, so pay close attention to.