Effects of different anti thrombotic strategies on bleeding risk, cardiac events and quality of life in elderly patients with acute non ST segment elevation myocardial infarction complicated with atrial fibrillation
10.3969/j.issn.1005-1678.2017.06.152
- VernacularTitle:不同抗栓策略联合心理干预对老年急性非ST段抬高心肌梗死合并心房颤动患者出血风险、心脏事件及生活质量的影响
- Author:
Haiyan CHEN
;
Kefeng SUN
- Keywords:
anti thrombosis;
elderly;
acute non ST segment elevation myocardial infarction;
atrial fibrillation;
bleeding risk;
cardiac events;
quality of life
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):397-399
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of different anti thrombotic strategies on the risk of bleeding, cardiac events and quality of life in elderly patients with acute non ST segment elevation myocardial infarction.MethodsElderly patients with acute non ST elevation myocardial infarction 200 cases of complication in patients with atrial fibrillation, are in our hospital from May 2013 to December 2015 were cardiovascular department, after discharge according to different antithrombotic strategy, according to the 5 groups, including 40 cases of A group, 75mg/d+ 100mg/d treatment with clopidogrel and aspirin;B group 40 cases.Using warfarin therapy;40 cases in group C, 75mg/d or 100mg/d+ with clopidogrel aspirin warfarin therapy;40 cases in group D, using 75mg/d+ 100mg/d+clopidogrel aspirin warfarin therapy, group E received 75mg/d+ clopidogrel aspirin 100mg/d plus warfarin therapy, based on the use of psychological intervention.The risk of bleeding, cardiac events and quality of life scores were compared.ResultsStatistical analysis showed that the incidence of major cardiac events in E group (2.5%) and the quality of life were optimal (the data are statistically significant compared to P<0.05, A, B);C, D, E groups, the risk of major bleeding rate compared with no significant difference.ConclusionThe application of drugs and psychological intervention in the treatment of elderly patients with acute non ST segment elevation myocardial infarction patients can be more effective.
