The clinical efficacy of treatment of subarachnoid hemorrhage with Danshen solution combine nimodipine
10.3969/j.issn.1005-1678.2017.06.047
- VernacularTitle:复方丹参注射液联合尼莫地平治疗蛛网膜下隙出血的临床疗效分析
- Author:
Xinqian YANG
;
Tao LI
;
Jinping LI
;
Qihuang ZHAO
- Keywords:
danshen solution;
nimodipine;
treatment of subarachnoid hemorrhage;
combination therapy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):126-128
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of treatment of subarachnoid hemorrhage with Danshen solution combine nimodipine.Methods80 cases diagnosis with subarachnoid hemorrhage from January 2014 to February 2015, were randomly divided into observation group and control group 40cases, observation group were plus conventional therapy Danshen solution treatment, the control group were given nimodipine only conventional treatment, recorded and analyzed before and after treatment S-100B protein in cerebrospinal fluid situation, status and treatment of disease incidence of complications in patients with two groups of patients.ResultsTreatment 5d, 7d, 14d after S-100B protein were observed in patients (0.788±0.014)μg/L,(0.625±0.15)μg/L,(0.501±0.13)μg/L, were better than the control group (0.957±0.16)μg/L,(0.823±0.17)μg/L,(0.711±0.12)μg/L, and the differences were statistically significant (P<0.05).Treatment observation group total effective rate of 90.0%, higher than 67.5%, and the difference was significant (P<0.05).The treatment group rebleeding, cerebral ischemia, hydrocephalus and other complications with the control group fairly, the difference was not significant.ConclusionIt is effective for the treatment of subarachnoid hemorrhage withdanshen solution combine nimodipine, can significantly improve the cure rate in patients with subarachnoid hemorrhage, reducing mortality.It is worthy of further research and applications.
