Effect of ritodrine hydrochloride on peripheral blood and tocolysis rate of patients with threatened premature labor
10.3969/j.issn.1005-1678.2017.06.126
- VernacularTitle:盐酸利托君对先兆早产患者外周血象及保胎率的影响
- Author:
Lili PAN
;
Jiangping SHI
;
Xiaomei LIU
- Keywords:
ritodrine hydrochloride;
threatened premature labor;
peripheral blood;
tocolysis
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(6):333-334,336
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of ritodrine hydrochloride on peripheral blood and tocolysis rate of patients with threatened premature labor.Methods89 cases of patients with threatened premature labor were selected from October 2015 to September 2016 and randomly divided into two groups, research group with 45 cases treated with ritodrine hydrochloride and control group with 44 cases treated with epsom salt.The peripheral blood, extinction time of uterine contraction, extended days of pregnancy, postpartum hemorrhage, neonatal birth weight and tocolysis rate were compared between two groups.ResultsAfter treatment, CRH, NO, PGE2 and IL-8 of control group were obviously higher than research group, the difference was statistically significant (t=10.826,3.839,7.534,8.075,P<0.05).The extinction time of uterine contraction in control group was obviously longer than research group, while extended days of pregnancy and neonatal birth days in research group were obviously longer than control group, the difference was statistically significant (t=4.566,7.855,3.237,P<0.05).There was no significant difference in postpartum hemorrhage between two groups (t=0.889,P>0.05).The overall efficacy of tocolysis in control group was 70.5%, while that in research group was 86.7%, which was obviously higher than the control group, the difference was statistically significant (χ2=7.801,P<0.05).ConclusionRitodrine hydrochloride can effectively control uterine contraction factor in peripheral blood and extend gestational days of patients with threatened premature labor, so as to improve tocolysis rate and birth quality.
