Immunometabolism and regulatory T cells
10.3760/cma.j.issn.0254-5101.2017.05.012
- VernacularTitle:免疫代谢与调节性T细胞
- Author:
Jiahe CHEN
;
Mei ZHANG
- Keywords:
Immunometabolism;
Regulatory T cell;
Metabolic disease
- From:
Chinese Journal of Microbiology and Immunology
2017;37(5):396-399
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies have shown that immune cells play an important role in the development of non-immune diseases.Regulatory T cells (Treg) are a group of T cell subsets which have immunoregulatory and immunosuppressive functions.Abnormalities in the number and function of Treg cells may cause immune imbalance, which leads to the development of diseases.Immunometabolic disorders may in turn affect the generation, proliferation and function of Treg cells.Clarification of the relationship and interaction between immunometabolism and Treg cells will make it possible to treat metabolic diseases with cellular immunotherapy.