Progress of multi-drug resistant bacteria and clinical treatment strategies

VernacularTitle:多重耐药菌现状及临床治疗策略研究进展
Author: Qi HUANG ; Lixing TIAN ; Xiaoying ZHOU ; Tao CHEN ; Huaping LIANG
Keywords: Multi-drug resistant bacteria; Antibiotics; Antibiotic resistance; Treatment strategy
From: Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2017;24(3):328-332
CountryChina
Language:Chinese
Abstract: Over the past two decades, multiple drug-resistant infections have escalated globally with the significantly increased morbidity and mortality due to the unreasonable uses of antimicrobial agents in areas such as animal husbandry, industry and medicine. As the situation of drug resistance has been progressively serious, anti-drug-resistant clinical strategies have attracted widely social concerns. This review will report the current status of antibiotic resistance and the mechanism of antibiotic-resistance all over the world. The anti-drug resistance strategies are the emphasis of our report, including the new indication of old antibiotics, the combination of existing antibiotics, the development of new antibiotics, nano-antibiotics, and non-infection treatment with immunomodulators and phage. This review aims to further understand the current situation of drug resistance, which optimizes the strategies of drug-resistant bacteria and clinical services.