Study on Related Factors of ACEI/ARB Drug Use in Hypertension Outpatients with Coronary Heart Dis-ease from a Hospital
10.6039/j.issn.1001-0408.2017.23.09
- VernacularTitle:某院门诊高血压合并冠心病患者应用ACEI/ARB类药物的相关因素研究
- Author:
Jun GUO
;
Fengtian HUANGFU
;
Longqian TANG
- Keywords:
ACEI;
ARB;
Hypertension;
Coronary heart disease
- From:
China Pharmacy
2017;28(23):3201-3203
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study related factors of ACEI/ARB drugs in hypertension patients with coronary heart disease. METHODS:Six hundred hypertension patients with coronary heart disease were selected from a hospital during Jan. 2012-Jan. 2015,310 patients receiving ACEI/ARB drugs were included in observation group,and 290 patients not receiving these drugs were included in control group. General information and lab indexes of 2 groups were collected and analyzed. RESULTS:There were sta-tistical significances in ambulatory arterial stiffness indexes [(0.57±0.13),(0.40±0.11)],24 h average systolic blood pressure [ (146.42±11.24)mmHg,(132.31±9.85)mmHg],24 h average diastolic blood pressure [(78.14±9.21)mmHg,(82.79±8.33) mmHg],24 h ambulatory pulse pressure [(64.89±13.57)mmHg,(53.54±9.78)mmHg],drinking rate(58.71%,28.28%),moder-ate intensity rate(31.29%,65.17%),BMI[(33.28±2.07)kg/m2,(23.17±2.86)kg/m2],LVEF [(35.65±11.42)%,(48.01± 12.45)%],dyslipidemia rate(66.77%,30.34%),myocardial infarction rate(68.39%,39.66%),revascularization rate(69.68%, 33.10%)and duration of coronary heart disease between 2 groups(P<0.05). The duration of coronary heart disease,dyslipid-emia,myocardial infarction,revascularization were included in multivariate Logistic regression analysis,with statistical signifi-cance(P<0.05). CONCLUSIONS:The application of ACEI/ARB drugs in hypertension patients complicated with coronary heart disease is influenced by many factors;dyslipidemia,myocardial infarction and revascularization are positive independent influential factors of ACEI/ARB drug use in the treatment,but drug use rate will decline with the duration increase.
