Comparison between indocyanine green fluorescence imaging plus methylene blue and plus carbon nanoparticles suspension injection for sentinel lymph node biopsy in breast cancer patients
- VernacularTitle:吲哚菁绿荧光成像联合亚甲蓝与纳米炭在乳腺癌前哨淋巴结活检中的对比
- Author:
Weiwei ZOU
;
Yu BAI
;
Xilong WANG
;
Kai CHENG
;
Hongguang SUN
;
Mengmeng WU
;
Jingru JIANG
;
Zhenlin YANG
- Keywords:
Breast neoplasms;
Sentinel lymph node biopsy;
Indocyanine green;
Methylene blue;
Carbon nanoparticles suspension injection
- From:
The Journal of Practical Medicine
2017;33(11):1857-1860
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the differences between indocyanine green (ICG) fluorescence imaging plus methylene blue and plus Carbon Nanoparticles Suspension Injection for sentinel lymph node biopsy (SLNB)in breast cancer patients. Methods A total of 134 cases of early breast cancer patients performed SLNB from November 2013 to November 2016 were involved,of which 48 cases were performed with ICG fluorescence imaging plus methylene blue,and another 86 cases plus Carbon Nanoparticles Suspension Injection. Results There was no significant difference between ICG plus Methylene Blue group and ICG plus nano carbon group in terms of detection rate(P>0.05),detected numbers(P>0.05),sensitivity(P>0.05),accuracy(P>0.05)and false negative rate(P > 0.05). Age,and body mass index(BMI)exerted no influence on the detection rate and accuracy of SLNB in two groups(P>0.05). Conclusion ICG Fluorescence Imaging plus Methylene Blue showed similar detection rate , detected numbers , sensitivity , accuracy and false negative rate as it plus Carbon Nanoparticles Suspension Injection for SLNB in breast cancer patients ,and both of them can be performed easily and conveniently.
