Progress in the research of tumor adoptive cellular immunotherapy
- VernacularTitle:肿瘤过继性细胞免疫治疗的研究进展
- Author:
Ruling WANG
;
Yongna WU
;
Liming WANG
;
Ying LI
;
Xiang YAN
- Keywords:
tumor;
immunotherapy;
genetic modification;
T lymphocyte
- From:
Basic & Clinical Medicine
2017;37(7):1055-1058
- CountryChina
- Language:Chinese
-
Abstract:
Adoptive immune cells can regulate and strengthen immune function of cancer patients,thus effectively inhibit tumor escaping.Cytokine induced killer cells (CIK),natural killer cells (NK),tumor infiltrating lymphocytes (TIL),dendritic cells (DC),T cell receptor-modified T cells (TCR-T) and chimeric antigen receptor-modified T cells (CAR-T) eliminate tumor by killing tumor cells directly or stimulating the immune response against tumor cells through different mechanisms.
