Analysis of amplitude of low-frequency fluctuation in patients with anxiety after radiofrequency catheter ablation by resting state fMRI
10.13929/j.1672-8475.201702001
- VernacularTitle:心律失常射频消融术后焦虑状态患者的静息态MRI低频振幅分析
- Author:
Jianping YANG
;
Guiwen LYU
;
Yi LEI
;
Jun XIA
;
Fan LIN
- Keywords:
Radiofrequency catheter ablation;
Anxiety disorder;
Amplitude of low-frequency fluctuation;
Magnetic resonance imaging
- From:
Chinese Journal of Interventional Imaging and Therapy
2017;14(8):472-475
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe brain functional activity of patients with arrhythmia after radiofrequency ablation with amplitude of low-frequency fluctuation (ALFF).Methods Twenty-six patients with anxiety disorder after radiofrequency catheter ablation (RFCA) were included as RFCA group.Age and sex matched twenty-six healthy volunteers were included as control group.The difference of ALFF between the two groups was analyzed by two-sample t test.Partial correlation between extracted values from dysfunctional brain regions and hamilton anxiety scale (HAMA) scores were investigated.Results Compared with control group,ALFF of left middle temporal gyrus,right putamen,left amygdala significantly increased,and left dorsolateral prefrontal cortex (DLPFC),right praecuneus,left middle frontal gyrus and right middle occipital gyus significantly decreased in RFCA group (Alphasim correction,P＜0.01).ALFF values of left DLPFC were negatively correlated with HAMA scores (r=-0.872,P=0.013).Conclusion The brain activity of RFCA patients in resting state is abnormal.ALFF can provide more evidences for the pathogenesis of the disease.
