Application of MRI histogram analysis in assessment risk of medulloblastoma recurrence

VernacularTitle:MRI灰度直方图分析在髓母细胞瘤复发风险评估中的应用
Author: Chendi ZHU ; Yong ZHANG ; Jingliang CHENG ; Ya LI ; Anke DONG ; Ruiping ZHENG
Keywords: Medulloblastoma; Recurrence; Histogram analysis; Magnetic resonance imaging
From: Chinese Journal of Interventional Imaging and Therapy 2017;14(8):480-483
CountryChina
Language:Chinese
Abstract: Objective To explore the value of MRI histogram analysis in the risk assessment of medulloblastoma recur rence.Methods The data of 28 patients pathologically confirmed of medulloblastoma was analyzed retrospectively.All patients were divided into recurrent group and the non recurrent group (each n=14).The ROIs were drawn on the maximum level of enhanced MR sagittal images,and the histogram analysis were performed using the software named Mazda.The statistical analysis was performed on the histogram parameters to find out the different characteristics between the two groups,and the ROC curve was drawn to evaluate its diagnostic efficacy for recurrence of medulloblastoma.Results In all of the 9 parameters which are extracted from histogram,kurtosis had statistical significance between the 2 groups (P=0.018).The area under the ROC curve was 0.776 (P=0.018),and the sensitivity and specificity of kurtosis in the risk assessment of medulloblastoma recurrence were 64.3％ and 71.4％,respectively.Conclusion MRI histogram analysis can be an important method to assess the risk of medulloblastoma recurrence.