To assess the effectiveness of the artesunate in 7-day treament course for uncomplicated P.falciparum malaria in Phuoc Hoa and Phuoc Thang communes, Bac Ai district, Ninh Thuan province
- Author:
Nong Thi Tien
- Publication Type:Journal Article
- Keywords:
Malaria
- MeSH:
Malaria;
Malaria,;
Falciparum;
Artemisinins
- From:Journal of Malaria and parasite diseases Control
2004;0(3):44-47
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The study was conducted to assess the effectiveness of the artesunate in 7-day treatment course on uncomplicated P.falciparum malaria from August to December 2003, in the Phuoc Hoa and Phuoc Thang communes, Bac Ai district, Ninh Thuan province. The clinical trials were implemented in conformity with the WHO Guidelines 2001. Artesunate with total dose of 16 mg/kg body weight was used for 7days in 159 patients with uncomplicated P. falciparum malaria. The oral treatment of patients was supervised strictly; the clinical assessment and parasite density were followed up during 28 days after treatment. The number of patients completing 28-day follow-up was 131 cases. The trial results showed that the success rate of treatment was 122/131 (accounting for 93.1%) cases, the mean fever clearance time (mean +/- SD) was 1.2:+/- 0.4 days, the mean parasite clearance time was 1.8+/- 0.7 days and the rate of late treatment failure was 9/131 cases (6.9%)
