Immediate rule-out of acute myocardial infarction using low risk electrocardiogram and baseline high-sensitivity troponin T in chest pain patients
10.3969/j.issn.1006-5725.2017.15.039
- VernacularTitle:低风险心电图联合初次超敏肌钙蛋白T水平早期排除胸痛患者中的急性心肌梗死
- Author:
Ying GUO
;
Xiangyang DU
;
Xin NIE
;
Yong HE
;
Xiaoling LI
;
Guixing LI
- Keywords:
acute myocardial infarction;
electrocardiogram;
high-sensitivity troponin T
- From:
The Journal of Practical Medicine
2017;33(15):2573-2576
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of this study was to evaluate the negative predictive value (NPV) and Sensitivity(Sen) of ruling out acute myocardial infarction(AMI) using low risk electrocardiogram(ECG) and baseline high-Sensitivity troponin T(hs-cTnT) immediately in chest pain patients. Methods Patients presenting to chest pain center with complain of chest pain in West China hospital of Sichuan university were enrolled. Clinical data including ECG and hs-cTnT concentration were gained .According to different diagnosis cutoff point, the NPV and Sen of ruling out AMI using low risk ECG and baseline hs-cTnT immediately in chest pain patients were evaluated. Results An hs-cTnT cutoff of 5 ng/L resulted in a NPV of 99.9%ruling out of all non-AMI patients. Adding the information of a low risk ECG resulted in a 100%NPV (19.51%ruled out). At any diagnosis cutoff point, present hs-cTnT concentration can not rule out AMI completely . Adding the information of a low risk ECG , the NPV of present hs-cTnT was improved and more non-AMI patients were ruled out safely. Conclusions It is safe to rule out AMI among the chest pain patients when the level of hs-cTnT less than 5 ng/L combined with low risk electrocardiogram.