Clinical managements of therapeutic hypothermia in newborns with hypoxic-ischemic encephalopathy

VernacularTitle:新生儿缺氧缺血性脑病低温治疗期间临床管理
Author: Suhua XU ; Guoqiang CHENG
Keywords: Therapeutic hypothermia; Hypoxic-ischemic encephalopathy; Neonatal intensive care unit; Brian damage; Asphyxia
From: Chinese Journal of Applied Clinical Pediatrics 2017;32(14):1116-1120
CountryChina
Language:Chinese
Abstract: Therapeutic hypothermia is believed to improve neurodevelopment outcome of infants with moderate-to-severe hypoxic-ischemic encephalopathy(HIE),however,the severe brain injury and neurologic sequelae still can be observed in some infants received therapeutic hypothermia.Optimal monitor and management of systematic complications presented by infants during cooling treatment are necessary for improvement of overall outcome.Therefore,it is essential to understand the functional change of each system of the whole body,to adapt adequate diagnostic methods and to train multidisciplinary staffs to monitor and manage moderate-to-severe HIE infants during therapeutic cooling.With the development of therapeutic hypothermia,it is currently considered as a standard of care for infants with moderate-to-severe HIE.It is recommended that any neonatal intensive care unit(NICU) using routinely therapeutic hypothermia to reference the national or international benchmarking protocols in order to improve the medical quality and prognosis of infants.