The impact of splenectomy and esophagogastric devascularization on the nutrition status of patients with cirrhosis and portal hypertension
10.3760/cma.j.issn.1007-8118.2017.07.002
- VernacularTitle:脾切除联合门奇静脉断流术对肝硬化合并门静脉高压症患者近远期营养状况的影响
- Author:
Daobing ZENG
;
Chun ZHANG
;
Liang DI
;
Daming GAO
;
Binwei DUAN
;
Haitao ZHANG
;
Qingliang GUO
;
Qinghua MENG
;
Lei LI
;
Juan LI
;
Xiaofei ZHAO
;
Jushan WU
;
Dongdong LIN
;
Yunjin ZANG
;
Zhaobo LIU
;
Libo SUN
;
Shichun LU
- Keywords:
Splenectomy;
Devascularization;
Cirrhosis;
Portal hypertension;
Nutritional status
- From:
Chinese Journal of Hepatobiliary Surgery
2017;23(7):437-440
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the impact of splenectomy and esophagogastric devascularization on the nutritional status of patients with cirrhosis and portal hypertension.Methods Sixty consecutive patients with cirrhosis and portal hypertension who underwent splenectomy and esophagogastric devascularization at the Beijing YouAn Hospital from April 5,2015 to January 23,2017 were included in this study.The body mass index (BMI),albumin (Alb),prealbumin (PA) and lymphocyte counts were prospectively collected at the end of 1-week,1-month,3-month,6-month and 1-year after surgery.The postoperative results were compared with the preoperative results in these patients.Results The BMI results obtained at 1-week and 1-month after surgery were significantly lower than the preoperative level [(22.14 ± 3.08)kg/m2 vs.(22.85 ± 3.14) kg/m2,(21.72 ± 3.05) kg/m2 vs.(22.86 ± 3.16) kg/m2,P ＜ 0.05].The BMI result at the end of 1-year after surgery was significantly elevated when compared with the preoperative level [(23.24 ± 3.64) kg/m2 vs.(22.68 ± 3.47) kg/m2,P ＜ 0.05].The ALB levels at 1-month and 3-month after surgery were significantly higher than the preoperative level [(39.87 ± 4.22)g/L vs.(35.35 ±5.15) g/L,(39.35 ± 4.75) g/L vs.(34.82 ± 5.50) g/L,P ＜ 0.05].The PA obtained at 1-week after surgery was significantly lower than the preoperative levels [(79.59 26.52)mg/L vs.(121.77 ±39.96)mg/L,P ＜ 0.05].The lymphocyte counts at all the points after surgery were significantly higher than the preoperative level (P ＜ 0.05).Conclusion Short term and long term nutritional status improved in patients with cirrhosis and portal hypertension after splenectomy and esophagogastric devascularization.
