Research progress on thyroglobulin and its antibody
10.16571/j.cnki.1008-8199.2017.08.018
- VernacularTitle:甲状腺球蛋白及其抗体研究进展
- Author:
Na LI
;
Fan YANG
- Keywords:
Autoimmune thyroid diseases;
Throglobulin;
Throglobulin gene;
Throglobulin autoantibodies
- From:
Journal of Medical Postgraduates
2017;30(8):869-872
- CountryChina
- Language:Chinese
-
Abstract:
Tg gene polymorphism, HLA and iodine interaction with Tg may be involved in the pathogenesis of autoimmune thyroid disease.Moreover, thyroglobulin antibody (TgAb), an important symbol of autoimmune thyroid disease, is also closely related to the development of autoimmune thyroid disease.In addition, the differences of TgAb IgG isoforms expression level also have broad application prospects in the classification and diagnosis of autoimmune thyroid disease.By researching on Tg, we review the pathogenesis of autoimmune thyroid disease and provided the evidence for its diagnosis and clinical treatment.
