Effect of Yiqixue Buganshen Recipe on the level of serum VEGF in high-risk patients with ovarian hyper- stimulation syndrome
10.3969/j.issn.1006-5725.2017.16.047
- VernacularTitle:益气血补肝肾中药对卵巢过度刺激综合征患者血管内皮生长因子的影响
- Author:
Xiaoyan CHEN
;
Weimin DENG
;
Xinyu GUO
;
Jinyu ZHANG
- Keywords:
Yiqixue Buganshen recipe;
ovarian hyperstimulation syndrome;
vascular endothelial growth factor
- From:
The Journal of Practical Medicine
2017;33(16):2788-2791
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of the Yiqixue Buganshen Recipe(YBR)on the level of serum VEGF in high-risk patients with OHSS. Method 298 infertile women with high-risk OHSS in the reproductive centre of our hospital from June to November ,2016 were enrolled into the traditional Chinese medicine (TCM) group (n = 148) and the control group(n = 150). 145 infertile women without high-risk OHSS were enrolled into the normal group. All the patients received the long protocol treatment ,and patients in the TCM group received the YBR treatment. Results Patients have higher quality embryo rate ,lower moderate and more severe OHSS rate in the TCM group compared with the control group(P<0.05). Patients in the normal group have lower serum VEGF compared with patients in the other 2 groups on the all three days. Patients in the TCM group has lower serum VEGF on the day of embryo transfer compared with patients in the control group(P<0.05). Conclusions The increment of the serum VEGF level is closely related to OHSS. The YBR may reduce the rate of moderate and severe OHSS by reducing the serum VEGF level on the day of embryo transfer ,which may prevent the moderate and severe OHSS of the high-risk patients.
