Atypical Femoral Fracture Combined with Osteonecrosis of Jaw During Osteoporosis Treatment with Bisphosphonate.
10.11005/jbm.2014.21.2.155
- Author:
Yougun WON
1
;
Joon Ryul LIM
;
Young Hwan KIM
;
Hyung Keun SONG
;
Kyu Hyun YANG
Author Information
1. Department of Orthopaedic Surgery, Konyang University College of Medicine, Daejeon, Korea.
- Publication Type:Case Report
- Keywords:
Atypical femoral fracture;
Bisphosphonate
- MeSH:
Aged;
Female;
Femoral Fractures*;
Humans;
Jaw*;
Osteonecrosis*;
Osteoporosis*;
Osteoporosis, Postmenopausal
- From:Journal of Bone Metabolism
2014;21(2):155-159
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bisphosphonate, a potent anti-resorptive agent, is generally accepted as a safe, effective, well tolerated treatment for postmenopausal osteoporosis. Atypical femoral fracture (AFF) and bisphosphonate related osteonecrosis of jaw (BRONJ) are the increasing morbidities in patients treated with long term bisphosphonate. Pathogenic mechanisms of AFF and BRONJ are not fully identified and not identical. We report a case of BRONJ followed by AFF and its nonunion in a 67-year-old woman patient receiving an oral bisphosphonate during 7 years for the treatment of osteoporosis.
