Clinical significance of serum PLA2R antibody and THSD7A antibody in idiopathic membranous nephropathy
10.3760/cma.j.issn.1009-9158.2017.08.003
- VernacularTitle:血清PLA2R抗体及THSD7A抗体对特发性膜性肾病的临床意义
- Author:
Qiuxia HAN
;
Hanyu ZHU
- Keywords:
Glomerulonephritis,membranous;
Receptors phospholipase A2;
Tthrombospondins;
Autoantibodies
- From:
Chinese Journal of Laboratory Medicine
2017;40(8):564-568
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the diagnosis of idiopathic membranous nephropathy (IMN) has been more and more important with the rapid growth rate on incidence in China.Previous diagnosis of IMN depends on renal biopsy, a gold standard, but a high risk of traumatic examination.The detection of serum PLA2R antibody and THSD7A antibody to assist in the diagnosis of is not only fast, sensitive, simple and noninvasive, but also can reflect the immune status in real time.Compared with the traditional proteinuria severity based therapeutic efficacy evaluation, that is more effective and agile to monitor the disease condition, reflect the treatment effects and predict the prognosis better.Therefore, it should be vigorously promoted.
