Progress in microRNA as biomarker for the early diagnosis of acute kidney injury
10.3760/cma.j.issn.1009-9158.2017.08.016
- VernacularTitle:microRNA作为急性肾损伤早期诊断生物标志物的研究进展
- Author:
Yang ZHAO
;
Liyan CUI
- Keywords:
Acute kidney injury;
microRNAs;
Biological markers;
Early diagnosis
- From:
Chinese Journal of Laboratory Medicine
2017;40(8):633-636
- CountryChina
- Language:Chinese
-
Abstract:
In recent years the incidence of acute kidney injury (AKI) has increased, with a high mortality rate and poor prognosis.The key of improving the prognosis of AKI is early diagnosis and intervention.Due to the lack of biomarkers of early diagnosis in AKI, the effective early treatment is generally delayed.Traditional diagnosis biomarkers such as serum creatinine and blood urea are delayed and affected by various factors.Recently, some new potential early diagnostic biomarkers have been found.MicroRNA(hereinafter referred to as the miRNA) is a kind of endogenous non-coding small RNA, and studies have shown that it is related to the development of AKI.
