Clinicopathologic features of 9 cases of adult rhabdomyosarcoma

VernacularTitle:9例成人横纹肌肉瘤的临床病理学分析
Author: Yongheng SHI ; Manmei LONG ; Qiang LIU ; Xiaoyu CHEN
Keywords: rhabdomyosarcoma; adult; clinicopathology; immunohistochemistry; diagnosis; prognosis
From: Journal of Shanghai Jiaotong University(Medical Science) 2017;37(7):1015-1019
CountryChina
Language:Chinese
Abstract: Objective·To investigate the clinicopathologic characteristics and prognosis of adult rhabdomyosarcoma (RMS).Methods·The clinical and pathological data,immunohistochemical test results of 9 RMS were analyzed retrospectively.Results·The information of 6 males and 3 females were collected in this research,whose average age was (46.89+20.09) years old.The tumors had a wide range distribution.The subtypes of histology included 6 cases of embryonal RMS,1 case of alveolar RMS,1 case of spindle cell RMS and 1 case of pleomorphic RMS.Immunohistochemically study showed that 6 cases were myogenin positive,4 cases were MyoDl positive and 8 cases were desmin positive.During the follow-up period of the 7 cases,only 2 patients survived free of tumors,2 patients presented with tumor recurrence and metastasis after the operations,and 3 patients died of tumor.Conclusion·In this study,embryonaI RMS is the most common type,and immunohistochemistry test is helpful to diagnosis of RMS.