The prediction of SIRS criteria and C-reactive protein to severe infection in children with fever in pediatric emergency room
10.3760/cma.j.issn.1673-4912.2017.07.009
- VernacularTitle:SIRS标准及C-反应蛋白对儿科急诊发热患儿重症感染情况的判定及预测作用
- Author:
Yang HU
;
Chunfeng LIU
- Keywords:
Sepsis;
Systemic inflammatory response syndrome;
C-reactive protein;
Children;
Emergency room
- From:
Chinese Pediatric Emergency Medicine
2017;24(7):517-522
- CountryChina
- Language:Chinese
-
Abstract:
Objective As the diagnosis criteria of sepsis,the systemic inflammatory response syndrome(SIRS) has the predictive effect on severe infection.Groups abroad have reported that SIRS criteria is not suitable for the severe infection in emergency room.This article aimed at discussing whether the SIRS criteria and C-reactive protein(CRP) are suitable for the prediction of severe infection in our country.Methods We collected the patients in fever(T>37.5℃)arriving at Shengjing Hospital of China Medical University from October to December in 2015 and recorded the symptoms,signs and treatments,then we discussed the sensitivity and specificity of SIRS criteria in evaluating the severe inflammation.Results Three hundred and ninty-two patients met the SIRS criteria out of 784 patients involved,and 9 of them were in hospital,SIRS criteria had no relevance with the treatments(χ2=4.714,P=0.194),which showed that the SIRS criteria had low sensitivity and specificity in evaluating the severe infection.Taking CRP>8mg/L as unusual,363 patients had abnormal CRP,216 of them met the SIRS and 9 of them were in hospstal.CRP had relevance with the treatment of patients in fever(χ2=46.750,P<0.01),and SIRS combined with CRP had statistics meaning in choosing treatment of infectious patients(χ2=41.783,P<0.01).Conclusion SIRS may fail to diagnose the severe infection.But SIRS criteria combined with CRP has the predictitive effect on infection in pediatric emergency room to a certain extent.
