Analysis of prognosis of aged esophageal cancer patients after esophagectomy
10.3969/j.issn.1674-8115.2017.07.024
- VernacularTitle:高龄食管癌患者手术治疗的预后分析
- Author:
Yuming WANG
;
Xiaozhe QIAN
;
Ziang CAO
;
Xiaojing ZHAO
;
Qing YE
- Keywords:
esophageal cancer;
esophageal surgery;
prognosis
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2017;37(7):1020-1024
- CountryChina
- Language:Chinese
-
Abstract:
Objective·To investigate factors affecting the prognosis of aged esophageal cancer patients after esophagectomy.Methods·Clinical data of 103 aged patients (≥ 80 years old) undergoing esophageetomy were collected.Effects of age,sex,clinical manifestations,pre-operative diseases,post-operative complications,T stage,lymph node metastasis,maximum diameter and location of the tumor,and surgical methods on the post-operative survival were analyzed.Results·1,3,and 5 years survival rates of 103 patients were 63.2％,15.9％,and 2.7％,respectively.Kaplan-Meier survival curve analysis indicated that the post-operative survival was significantly higher in patients with T1 and T2 stages than in patients with T3 stage.The 3 and 5 y survival rates of patients with T 1 stage were 50％ and 25％,respectively.Results of Cox regression multivariate analysis showed that T stage,maximum diameter of tumor,postoperative complications,and lymph node metastasis were independent factors affecting the post-operative survival.Conclusion·Esophageal cancer patients aged over 80 years with smaller tumor diameters,less postoperative complications,and negative lymph node metastasis have a longer post-operative survival period.Esophagectomy for patients with earlier stages (T1 and T2) can achieve an ideal post-operative survival period.
