A survey on the hypoglycemic agents applied to diabetic inpatients in non-endocrinological wards of a comprehensive general hospital
10.3760/cma.j.issn.1000-6699.2017.07.001
- VernacularTitle:综合性医院非内分泌专科住院糖尿病患者降糖药物的应用情况调查
- Author:
Xiulian GU
;
Jingtao DOU
;
Weijun GU
;
Guoqing YANG
;
Jin DU
;
Kang CHEN
;
Lijuan YANG
;
Li ZANG
;
Xianling WANG
;
Nan JIN
;
Zhaohui LYU
;
Jianming BA
;
Yiming MU
;
Juming LU
;
Jiangyuan LI
;
Changyu PAN
- Keywords:
Hospitalization;
Diabetes mellitus;
Oral antidiabetic drugs;
Insulin
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(7):541-547
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the current status and trend of hypoglycemic agents of diabetic inpatients in different departments of Chinese PLA General Hospital.Methods The clinical data of diabetic patients admitted to Chinese PLA General Hospital from January 2000 to May 2014 were collected(those hospitalized in the department of endocrinology were excluded).A total of 10 041 patients were selected by stratified random sampling.The type of hypoglycemic agents in different departments and the variation on anti-hyperglycemic drugs with time were retrospectively analyzed.Results Of all the patients in non-endocrinological wards, 50.2% were treated with insulin, 36.9% with metformin, 21.3% with α-glycosidase inhibitor, and 18.9% with sulfonylureas.Metformin, α-glucosidase inhibitors, pre-mixed 30R, and insulin glargine were more commonly used than other anti-hyperglycemic agents, accounting for 36.9%, 21.0%, 14.0%, 8.7%, respectively.Metformin, sulfonylureas, α-glucosidase inhibitor, and different types of insulin were more widely applied in internal medicine while insulin therapy was more frequently used in surgical department.During the past 15 years, the proportions of insulin, glinides, α-glucosidase inhibitor, and thiazolidinediones application were gradually increased, while the proportions of sulfonylureas and metformin treatment were on the decline trend.Conclusion Most of the inpatients were treated with oral antidiabetic drugs.Metformin, α-glucosidase inhibitor, pre-mixed 30R, and insulin glargine were the most frequently prescribed agents for the inpatients.