Research progress on the relationship between Rho GTPases and breast cancer
10.11958/20170580
- VernacularTitle:Rho蛋白家族与乳腺癌关系的研究进展
- Author:
Xia ZHENG
;
Bingbing LIU
;
Fanfan MENG
;
Shuai LI
;
Feng GU
;
Li FU
- Keywords:
breast neoplasms;
neoplasm metastasis;
GTP-binding proteins;
Rho GTPases;
regulatory proteins;
Rho GTPases effectors;
targeted therapy
- From:
Tianjin Medical Journal
2017;45(7):777-780
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is one of the major causes of death in women,and its incidence has been increasing year after year.The Rho GTPases,their regulatory proteins and Rho GTPases play an important role in promoting the occurrence and distant metastasis of breast cancer.Here we summarized the current knowledge of the regulation network of Rho GTPases,their regulatory proteins and Rho GTPases on the occurrence and development of breast cancer,and targeted therapy for RHO GTP enzyme pathway in breast cancer.
